Bromocyclococanol, a halogenated sesquiterpene with a novel carbon skeleton from the red alga Laurencia obtusa

3 pages, 2 figures, 1 table.-- Printed version published Apr 1, 2002.
A bromo sesquiterpene, bromocyclococanol 1, containing fused cyclopropane–cyclopentane rings leading a novel carbon skeleton has been isolated from the red alga Laurencia obtusa. The structure and stereochemistry were established by spectroscopic evidence and biogenetic considerations. A biogenetic route for this compound has also been proposed.
The structure, configuration and possible biogenesis for bromocyclococanol 1 are described.
This work was supported by Ministerio de Ciencia y Tecnología (MCYT), FEDER (project 1FD97-0348- C03-03), Subdirección General de Cooperación Internacional, Program of Cooperation between the Consejo Superior de Investigaciones Científicas (CSIC, Spain)- Universidad de Chile and the collaboration of CEBIMAR of Cuba. I.B. acknowledges a grant from the MCYT.