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Examining key sociodemographic characteristics of adolescents and young adults with cancer: a post-hoc analysis of the Promoting Resilience in Stress Management (PRISM) randomized clinical trial
- Source :
- Palliat Med
- Publication Year :
- 2019
-
Abstract
- Background: The “Promoting Resilience in Stress Management” intervention is a skills-based, early palliative care intervention with demonstrated efficacy in adolescents and young adults with cancer. Aim: Utilizing data from a randomized clinical trial of Promoting Resilience in Stress Management versus Usual Care, we examined whether response to Promoting Resilience in Stress Management differed across key sociodemographic characteristics. Design: Adolescents and young adults with cancer completed patient-reported outcome measures of resilience, hope, benefit-finding, quality of life, and distress at enrollment and 6 months. Participants were stratified by sex, age, race, and neighborhood socioeconomic disadvantage based on home address (Area Deprivation Index scores with 8–10 = most disadvantaged). Differences in the magnitude of effect sizes between stratification subgroups were noted using a conservative cutoff of d > 0.5. Setting/participants: Participants were 12 to 25 years old, English-speaking, and receiving cancer care at Seattle Children’s Hospital. Results: In total, 92 adolescents and young adults (48 Promoting Resilience in Stress Management, 44 Usual Care) completed baseline measures. They were 43% female, 73% 12 to 17 years old, 64% White, and 24% most disadvantaged. Effect sizes stratified by sex, age, and race were in an expected positive direction and of similar magnitude for the majority of outcomes with some exceptions in magnitude of treatment effect. Those who lived in less disadvantaged neighborhoods benefited more from Promoting Resilience in Stress Management, and those living in most disadvantaged neighborhoods benefited less. Conclusion: The “Promoting Resilience in Stress Management” intervention demonstrated a positive effect for the majority of outcomes regardless of sex, age, and race. It may not be as helpful for adolescents and young adults living in disadvantaged neighborhoods. Future studies must confirm its generalizability and integrate opportunities for improvement by targeting individual needs.
- Subjects :
- Gerontology
Male
Stress management
Palliative care
Adolescent
media_common.quotation_subject
Psycho-oncology
Article
law.invention
03 medical and health sciences
Young Adult
0302 clinical medicine
Randomized controlled trial
law
Intervention (counseling)
Neoplasms
Post-hoc analysis
Medicine
Humans
030212 general & internal medicine
Young adult
Child
media_common
business.industry
Palliative Care
General Medicine
Resilience, Psychological
Psychotherapy
Anesthesiology and Pain Medicine
Socioeconomic Factors
030220 oncology & carcinogenesis
Quality of Life
Female
Psychological resilience
business
Stress, Psychological
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- Palliat Med
- Accession number :
- edsair.doi.dedup.....7b61a144affe4ac5ceb66294a97c004e