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Diffuse Large B-cell Lymphoma of Testis: a Case Report and Current Literature Review
- Source :
- Folia Medica, Vol 62, Iss 1, Pp 200-203 (2020)
- Publication Year :
- 2020
- Publisher :
- Pensoft Publishers, 2020.
-
Abstract
- Introduction: Testicular cancers detected in older males are mostly testicular lymphomas. Primary testicular lymphoma (PTL) is a rare, clinically aggressive form of extranodal lymphoma. In population-based studies, the incidence of PTL is 0.09-0.26/100.000. The vast majority of PTL are diffuse large B-cell lymphoma (DLBCL). Case presentation: We present a case of PTL diagnosed in a 68-year-old male patient and also, we discuss the incidence, clinical presentation, prognostic factors and management of this rare pathology in the light of current literature. Histopathological and immunohistochemical exams of the patient confirmed the diagnosis of DLBCL after radical orchiectomy. According to the internal prognostic index (IPI), patients’ IPI score was evaluated as 5 and according to Ann Arbor staging, patients’ stage was interpreted as grade 3E. Cyclophosphamide, vincristine, etoposide, and prednisolone chemotherapy was planned for the patient and until now, the patient received his first chemotherapy regimen. Discussion: Primary testicular lymphoma should be kept in mind for every patient who admits with a testicular mass, especially in advanced age. Misinterpreatation of the clinical findings can delay the definitive diagnosis. Primary testicular lymphoma should be managed with a multi-disciplinary team including urologists, medical and radiation oncologists.&nbsp
- Subjects :
- 0301 basic medicine
Male
Vincristine
medicine.medical_specialty
Ann Arbor staging
Cyclophosphamide
Prednisolone
Population
diffuse large B-cell
lcsh:Medicine
lymphoma
testis
03 medical and health sciences
0302 clinical medicine
Testicular Neoplasms
hemic and lymphatic diseases
Antineoplastic Combined Chemotherapy Protocols
Medicine
Humans
education
Etoposide
Aged
education.field_of_study
business.industry
lcsh:R
General Medicine
medicine.disease
Chemotherapy regimen
Lymphoma
030104 developmental biology
030211 gastroenterology & hepatology
Radiology
Lymphoma, Large B-Cell, Diffuse
business
Diffuse large B-cell lymphoma
Orchiectomy
medicine.drug
Subjects
Details
- Language :
- English
- ISSN :
- 13142143
- Volume :
- 62
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Folia Medica
- Accession number :
- edsair.doi.dedup.....7b31d52fa349ee9d24e8369213a6d5f6