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Ultrastructural changes in mouse liver cells: a morphometric study on the influence of morphine, heroin, and cardiostenol

Authors :
A Lambiase
Crowell J
G. D'alfonso
M. Piazza
N. Abrescia
W. Schreil
Cocchiararo M
Borgia G
Borgia, Guglielmo
J., Crowell
M., Cocchiararo
N., Abrescia
A., Lambiase
G., D'Alfonso
W., Schreil
M., Piazza
Publication Year :
1982

Abstract

In drug addicts viral hepatitis is more frequent, its course is longer, and the percentage of chronic complications is higher than in nonaddicts. In addition many apparently healthy addicts show evidence of hepatic disfunction when screened. The role of the drug and its contaminants in this medical situation is not clear. In this paper we describe the effect of morphine, heroin, and Cardiostenol on normal mouse liver ultrastructure using morphometric methods. A statistically significant increase in volume density and surface density of smooth endoplasmic reticulum has been observed.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....7ac7d444d4c74ff37d2b3ad29b8ae533