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New 24-Isopropylcholesterol and 24-Isopropenylcholesterol Sulfate from the Marine Sponge Epipolasis Species
- Source :
- Journal of Natural Products. 63:1175-1177
- Publication Year :
- 2000
- Publisher :
- American Chemical Society (ACS), 2000.
-
Abstract
- Two novel steroids, polasterol A (1) and polasterol B sulfate (2), along with two known compounds, 22(E),24-isopropylcholesta-5, 22-dien-3 beta-ol (3) and halistanol sulfate (4), have been isolated from the Japanese marine sponge Epipolasis sp. The structures of 1 and 2 were determined as 3 beta-hydroxy-24-isopropylcholesta-5, 22(E)-dien-7-one and 24xi-isopropenylcholesta-22(Z), 28(29)-diene-2 beta,3 alpha,6 alpha-triyl trisodium sulfate on the basis of spectroscopic investigations and a chemical conversion.
- Subjects :
- Magnetic Resonance Spectroscopy
Optical Rotation
Spectrophotometry, Infrared
Stereochemistry
medicine.medical_treatment
Pharmaceutical Science
Polasterol B sulfate
Gas Chromatography-Mass Spectrometry
Analytical Chemistry
Steroid
chemistry.chemical_compound
Epipolasis
Japan
Drug Discovery
medicine
Animals
Sulfate
Pharmacology
biology
Chemistry
Organic Chemistry
biology.organism_classification
Porifera
Sponge
Cholesterol
Complementary and alternative medicine
Chromatography, Gel
Molecular Medicine
Spectrophotometry, Ultraviolet
Steroids
Triol
Enone
24-isopropenylcholesterol
Subjects
Details
- ISSN :
- 15206025 and 01633864
- Volume :
- 63
- Database :
- OpenAIRE
- Journal :
- Journal of Natural Products
- Accession number :
- edsair.doi.dedup.....7abc013d6ddf1498d302519b41a7cd5c