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Migraine with Aura and Right-to-Left Shunt on Transcranial Doppler: A Case-Control Study
- Source :
- Cerebrovascular Diseases. 8:327-330
- Publication Year :
- 1998
- Publisher :
- S. Karger AG, 1998.
-
Abstract
- Right-to-left shunt (RLS), usually due to patent foramen ovale, is a well-established risk factor for ischemic stroke in young patients, while the role of migraine as an independent factor is still debated. We evaluated 44 patients suffering from migraine with aura, and compared them with 73 patients younger than 50 with focal cerebral ischemia, and 50 controls, asymptomatic for cerebrovascular disease, and without a history of migraine. All the subjects underwent bilateral transcranial Doppler with injection of contrast medium in an antecubital vein. The test was performed during normal ventilation and during Valsalva maneuver, recording both the middle cerebral arteries and the basilar artery. Criteria for diagnosing RLS was the presence of at least 3 microbubbles within 15 s from injection. Eighteen out of 44 migraine patients (41%) showed RLS, as opposed to 8 of 50 controls (16%) (p < 0.005). Twenty-six out of 73 patients with cerebral ischemia had RLS (35%). We conclude that the prevalence of RLS in patients with migraine with aura is significantly higher than in normal controls, and is similar to the prevalence of RLS in young patients with stroke. These findings could be helpful in understanding the relationship between migraine and stroke.
- Subjects :
- Adult
Male
medicine.medical_specialty
Adolescent
Ultrasonography, Doppler, Transcranial
Migraine Disorders
Right-to-left shunt
Heart Septal Defects, Atrial
Brain Ischemia
Perceptual Disorders
stomatognathic system
Internal medicine
medicine.artery
mental disorders
medicine
Humans
Heart septal defect
business.industry
Case-control study
Middle Aged
medicine.disease
Migraine with aura
Transcranial Doppler
Shunt (medical)
Neurology
Migraine
Case-Control Studies
Cerebrovascular Circulation
Cardiology
Patent foramen ovale
Female
Neurology (clinical)
medicine.symptom
Cardiology and Cardiovascular Medicine
business
Subjects
Details
- ISSN :
- 14219786 and 10159770
- Volume :
- 8
- Database :
- OpenAIRE
- Journal :
- Cerebrovascular Diseases
- Accession number :
- edsair.doi.dedup.....7a91fdd348e04b2d86cd60f18bbfac9f