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Age-specific risk of fetal loss observed in a second trimester serum screening population
- Source :
- American Journal of Obstetrics and Gynecology. 192:240-246
- Publication Year :
- 2005
- Publisher :
- Elsevier BV, 2005.
-
Abstract
- Objective The purpose of this study was to investigate age-specific spontaneous fetal loss rates of pregnancies without known chromosomal or structural abnormalities from mid-second trimester onward. Study design The study consisted of 264,653 women screened between October 1995 and September 2000 with available pregnancy outcomes. Pregnancies associated with fetal chromosomal or structural abnormalities, insulin dependent diabetes mellitus, and multiple pregnancies were excluded. Spontaneous fetal losses at or after 15 weeks of gestation were identified. Women were grouped according to maternal age at expected date of delivery. Spontaneous fetal loss rates in each group were evaluated after adjusting fetal losses associated with amniocentesis and identifiable ethnic groups. Results Fetal loss rates increased in both younger and older women. The lowest rate was seen in women at mid-20s. Compared with Caucasian and Asian women, black women had higher fetal loss rate at nearly every age group. Conclusion The results of the study provided a baseline age-specific spontaneous fetal loss rate of pregnancies at a specified gestational window.
- Subjects :
- Adult
medicine.medical_specialty
Adolescent
Population
Black People
Prenatal diagnosis
Age Distribution
Pregnancy
Risk Factors
Prenatal Diagnosis
Diabetes mellitus
medicine
Humans
Risk factor
education
Fetal Death
Ontario
Gynecology
Fetus
education.field_of_study
medicine.diagnostic_test
business.industry
Obstetrics
Age Factors
Pregnancy Outcome
Obstetrics and Gynecology
medicine.disease
Pregnancy Complications
Diabetes, Gestational
Pregnancy Trimester, Second
Amniocentesis
Gestation
Female
Down Syndrome
business
Maternal Age
Subjects
Details
- ISSN :
- 00029378
- Volume :
- 192
- Database :
- OpenAIRE
- Journal :
- American Journal of Obstetrics and Gynecology
- Accession number :
- edsair.doi.dedup.....7a53407328d851b175a5448c6e427006