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Developmental Changes in the Biliary Excretion of Methylmercury and Glutathione
- Source :
- Science. 216:61-63
- Publication Year :
- 1982
- Publisher :
- American Association for the Advancement of Science (AAAS), 1982.
-
Abstract
- The long half-time for methylmercury in the neonatal rats is explained by the neonatal liver's inability to secrete the toxin into bile, which in adults is the main route of elimination. The ability to secrete mercury into bile develops between 2 and 4 weeks of age and is correlated with the increasing ability of the developing liver to secrete glutathione into bile.
- Subjects :
- medicine.medical_specialty
chemistry.chemical_element
Biology
medicine.disease_cause
digestive system
chemistry.chemical_compound
Biliary excretion
Internal medicine
medicine
Animals
Bile
Secretion
Sulfhydryl Compounds
Methylmercury
Multidisciplinary
Toxin
Age Factors
Biological Transport
Glutathione
Methylmercury Compounds
Rats
Mercury (element)
Endocrinology
Liver
chemistry
Subjects
Details
- ISSN :
- 10959203 and 00368075
- Volume :
- 216
- Database :
- OpenAIRE
- Journal :
- Science
- Accession number :
- edsair.doi.dedup.....7a37ec7580b8cae250bcd5e72fb7959d