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Invasive lobular carcinoma of the breast presenting as retroperitoneal fibrosis: a case report
- Source :
- Journal of Medical Case Reports, Pathology Publications, Journal of Medical Case Reports, Vol 4, Iss 1, p 175 (2010)
- Publication Year :
- 2009
-
Abstract
- Introduction Invasive lobular carcinoma of the breast represents approximately 6.3% of mammary malignancies. Distant metastasis of invasive lobular carcinoma to the peritoneum or retroperitoneum has been reported fairly frequently. Case presentation We report the case of a 59-year-old Caucasian-Canadian woman with invasive lobular carcinoma of the breast presenting with retroperitoneal fibrosis and bilateral ureteral obstruction. Intra-operative pathology consultation did not reveal malignancy. The diagnosis, however, was confirmed on permanent sections by histological appearance in addition to immunohistochemistry. To the best of our knowledge, this is the first reported case of invasive lobular carcinoma of the breast presenting with retroperitoneal fibrosis. Conclusion In a case of unexplained ureteric obstruction and retroperitoneal fibrosis, more comprehensive physical examination and additional ancillary studies may be warranted to rule out malignancy as an underlying etiology. This case also emphasizes that intra-operative frozen section consultation cannot always be fully relied upon to exclude a malignancy as the etiology of retroperitoneal fibrosis. Moreover, in permanent histopathology sections, immunohistochemistry testing can be of value to rule out metastatic disease where the morphology is not salient. There is a need for a thorough physical examination of patients with retroperitoneal fibrosis, including the breast and gynecological organs.
- Subjects :
- medicine.medical_specialty
Pathology
Lobular carcinoma
lcsh:Medicine
Physical examination
Retroperitoneal fibrosis
Malignancy
Surgical oncology
Case report
medicine
Breast
skin and connective tissue diseases
Medicine(all)
medicine.diagnostic_test
business.industry
lcsh:R
General Medicine
medicine.disease
Invasive lobular carcinoma
Etiology
Histopathology
Surgery
medicine.symptom
business
Subjects
Details
- ISSN :
- 17521947
- Volume :
- 4
- Database :
- OpenAIRE
- Journal :
- Journal of medical case reports
- Accession number :
- edsair.doi.dedup.....79fdf1cd52164dd82270fe009caaffb2