Back to Search
Start Over
Nut Consumption and Renal Function Among Women With a History of Gestational Diabetes
- Source :
- Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation, vol 30, iss 5, J Ren Nutr
- Publication Year :
- 2020
- Publisher :
- eScholarship, University of California, 2020.
-
Abstract
- ObjectiveNut intake has been associated with reduced cardiometabolic risk, but few studies have examined its association with renal function. We examined associations between nut intake and renal function among women with previous gestational diabetes mellitus (GDM), a population with an increased risk for renal dysfunction.Design and methodsThis study included 607 women with a history of GDM who participated in the Diabetes & Women's Health Study (2012-2014) follow-up clinical examination in Denmark. At the clinic, biospecimens were collected, and habitual intake of nuts (9 types) in the past year was assessed using a food frequency questionnaire. A total of 330 women free of major chronic diseases were included in the analysis. Total nut intake was classified as none (≤1 serving/month), monthly (2-3 servings/month), weekly (1-6 servings/week), and daily (≥1 serving/day). One serving was defined as 28 g. Renal function markers included estimated glomerular rate (eGFR) and urinary albumin-to-creatinine ratio (UACR), calculated based on plasma creatinine (mg/dL), and urinary albumin (mg/L), and creatinine (mg/dL) measurements, respectively. We estimated percent differences with 95% confidence intervals for each outcome by nut intake, adjusted for current body mass index, age, physical activity, energy intake, alcohol consumption, and vegetables intake.ResultsWe observed a nonlinear association between total nut intake and UACR with lowest UACR values among women with weekly intake. Compared to women with weekly intake (n=222), the adjusted UACR values were higher by 86% [95% confidence interval: 15%, 202%], 24% [-1%, 54%], and 117% [22%, 288%] among women with no (n=13), monthly (n=86), and daily (n=9) intake, respectively. Compared to weekly consumers, daily nut consumers also had 9% [0%, 19%] significantly higher eGFR values, but eGFR values were similar among women with no and monthly intake.ConclusionModerate nut consumption may be beneficial to kidney health among women with prior GDM.
- Subjects :
- 0301 basic medicine
Kidney Disease
Denmark
030232 urology & nephrology
Medicine (miscellaneous)
Kidney
Cohort Studies
chemistry.chemical_compound
0302 clinical medicine
Pregnancy
Nuts
Longitudinal Studies
education.field_of_study
Nutrition and Dietetics
Diabetes
Middle Aged
Urology & Nephrology
Gestational diabetes
Nephrology
Gestational
Kidney Diseases
Female
Cohort study
Glomerular Filtration Rate
Adult
medicine.medical_specialty
Population
Clinical Sciences
Renal and urogenital
Renal function
Article
03 medical and health sciences
Clinical Research
Diabetes mellitus
Internal medicine
medicine
Humans
education
Metabolic and endocrine
Nutrition
Creatinine
030109 nutrition & dietetics
business.industry
Prevention
medicine.disease
Confidence interval
Diet
Diabetes, Gestational
chemistry
business
Body mass index
Subjects
Details
- Database :
- OpenAIRE
- Journal :
- Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation, vol 30, iss 5, J Ren Nutr
- Accession number :
- edsair.doi.dedup.....79e72951b8d4d4efa6b216711b0f9560