Fertility Outcomes after Surgical Management of Colorectal Endometriosis: A Single-center Retrospective Study

To assess the pregnancy rate after surgery for colorectal endometriosis.A retrospective, single-centre study performed from January 2014 to December 2019.A university tertiary referral centre.Patients with the intention to get pregnant under the age of 43 years, with or without a history of infertility and who were surgically managed for colorectal endometriosis.Complete excision of deeply infiltrating endometriosis (DIE).The postoperative pregnancy rate was assessed. Seventy-seven patients had surgery; their mean age was 32.5 ± 4.4 years. Preoperative documented infertility was present in 77.9% (n = 60) of patients. The mean length of history of infertility was 36.2 ± 24.9 months. The procedure was performed by laparoscopic surgery in 92.2% (n = 71) of patients. Non-conservative, conservative and mixed treatment were performed in 66.2% (n = 51), 29.9% (n = 23) and 3.9% (n = 3) of patients, respectively. According to the Clavien-Dindo classification, the 3B complication rate was 6.5% (n = 5). The mean follow-up was 46.7 ± 20.6 months. Clinical pregnancies were defined by the presence of intra-uterine pregnancy with an embryo with cardiac activity. The postoperative pregnancy rate was 62.3% (n = 48), and 54.2% (n = 26) were spontaneous. The mean number of pregnancies was 1.2 ± 0.4 per patient. In addition, 18.7% (n = 9) of patients got pregnant twice. The mean time from surgery to pregnancy was 13.8 ± 13.1 months. The live birth rate was 89.1% (n = 41). There were no significant differences concerning the prognostic criteria reported in the literature (anti-Müllerian hormone level, age, presence of adenomyosis). There were no predictive criteria for live births.According to this study, surgery for colorectal endometriosis results in a high postoperative pregnancy rate. Studies with a high level of evidence are needed to determine good candidates for this type of surgery.