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Storage time of red blood cells among ICU patients with septic shock
- Source :
- Acta anaesthesiologica ScandinavicaREFERENCES. 63(10)
- Publication Year :
- 2019
-
Abstract
- Background We aimed to describe the exposure to blood transfusions and mortality among patients with septic shock. Methods We did a retrospective cohort study of two cohorts-patients with septic shock registered in a Danish ICU database (2008-2010) and patients from the Transfusion Requirements in Septic Shock (TRISS) trial (2011-2013). We extracted information on blood transfusions issued to all patients. We investigated the number of patients receiving very fresh blood (less than 7 days), very old blood (more than 24 days) and blood with a mixture of storage time. Results In the Danish cohort, 1637 patients were included of whom 1394 (85%) received 20,239 blood units from 14 days prior the ICU admission to 90 days after; 33% were transfused before, 77% in the ICU and 36% after ICU. The exposure to exclusively very fresh or very old blood was 3% and 4%, respectively. In the TRISS cohort, 77% of the 937 patients received 5047 RBC units; 3% received exclusively very fresh and 13% very old blood. The point estimate of mortality was higher among patients receiving large amounts of exclusively very fresh and very old blood, but the number of patients were very small. Conclusions Patients with septic shock were transfused both before and after ICU. Exposure to blood of less than 7 days or more than 24 days old were limited. We were not able to detect higher mortality among the limited number of patients with septic shock transfused with very fresh or very old blood.
- Subjects :
- Male
Icu patients
medicine.medical_specialty
Time Factors
03 medical and health sciences
0302 clinical medicine
medicine
Humans
030212 general & internal medicine
Aged
Retrospective Studies
Septic shock
business.industry
030208 emergency & critical care medicine
Retrospective cohort study
General Medicine
Middle Aged
medicine.disease
Shock, Septic
3. Good health
Icu admission
Intensive Care Units
Anesthesiology and Pain Medicine
Blood Preservation
Cohort
Emergency medicine
Blood units
Female
business
Erythrocyte Transfusion
Subjects
Details
- ISSN :
- 13996576 and 20082010
- Volume :
- 63
- Issue :
- 10
- Database :
- OpenAIRE
- Journal :
- Acta anaesthesiologica ScandinavicaREFERENCES
- Accession number :
- edsair.doi.dedup.....798666a6d7eb0114066176b39aea1f5b