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Right ventricular end-systolic remodeling index in the assessment of pediatric pulmonary arterial hypertension. The European Pediatric Pulmonary Vascular Disease Network (EPPVDN)
- Source :
- Pediatric Research. 88:285-292
- Publication Year :
- 2020
- Publisher :
- Springer Science and Business Media LLC, 2020.
-
Abstract
- Echocardiographic determination of the right ventricular end-systolic remodeling index (RVES RI) has clinical value for the assessment of pulmonary hypertension (PH) in adults. We aim to determine RVES RI values in pediatric PH and to correlate RVES RI data with echocardiographic variables and NYHA functional class (FC). Prospective echocardiography study in 49 children with PH. The 49 matched control subjects were chosen from 123 healthy children used to construct pediatric normal reference values. The associations with invasive hemodynamic variables were also investigated in a validation cohort of 12 PH children and matched controls. RVES RI was increased in children with PH vs. healthy controls (1.45 ± 0.16 vs. 1.16 ± 0.06; p
- Subjects :
- Male
Pulmonary Circulation
medicine.medical_specialty
Adolescent
Systole
Heart Ventricles
Hypertension, Pulmonary
Hemodynamics
Pulmonary Artery
03 medical and health sciences
0302 clinical medicine
Reference Values
030225 pediatrics
Internal medicine
medicine.artery
medicine
Humans
Prospective Studies
Vascular Diseases
Child
Pulmonary Arterial Hypertension
Ventricular Remodeling
business.industry
Vascular disease
Matched control
Infant, Newborn
Infant
medicine.disease
Pulmonary hypertension
Blood pressure
ROC Curve
Echocardiography
Case-Control Studies
Child, Preschool
Reference values
Pressure load
Pediatrics, Perinatology and Child Health
Pulmonary artery
Ventricular Function, Right
Cardiology
Female
business
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 15300447 and 00313998
- Volume :
- 88
- Database :
- OpenAIRE
- Journal :
- Pediatric Research
- Accession number :
- edsair.doi.dedup.....798605a115c565abe709613a7d0c6415