Photocatalytic Azetidine Synthesis by Aerobic Dehydrogenative [2 + 2] Cycloadditions of Amines with Alkenes

Authors :: Rajesh Dasi
Alexander Villinger
Malte Brasholz
Source :: Organic Letters. 24:8041-8046
Publication Year :: 2022
Publisher :: American Chemical Society (ACS), 2022.
Abstract: Photocatalytic dehydrogenative [2 + 2] cycloadditions between amines and alkenes were developed that allow for the stereoselective and high-yielding synthesis of functionalized azetidines. The oxidative formal Aza Paternò-Büchi reactions are induced by photoredox-catalyzed aerobic oxidation of dihydroquinoxalinones

Subjects :: Cycloaddition Reaction
Molecular Structure
Cyclization
Organic Chemistry
Azetidines
Alkenes
Amines
Physical and Theoretical Chemistry
Biochemistry
Catalysis

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