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Successful recovery from severe COVID‐19 pneumonia after kidney transplantation: The interplay between immunosuppression and novel therapy including tocilizumab

Authors :
Leonardo Centonze
Angelo Calini
Roberto Fumagalli
Marco Merli
Sara Santambrogio
Mila Valsecchi
Massimo Puoti
Riccardo De Carlis
Luciano De Carlis
Vincenzo Buscemi
Andrea Lauterio
Maurizio Bottiroli
Lauterio, A
Valsecchi, M
Santambrogio, S
De Carlis, R
Merli, M
Calini, A
Centonze, L
Buscemi, V
Bottiroli, M
Puoti, M
Fumagalli, R
De Carlis, L
Source :
Transplant Infectious Disease
Publication Year :
2020
Publisher :
Wiley, 2020.

Abstract

Although immunosuppressed patients may be more prone to SARS‐CoV‐2 infection with atypical presentation, long‐term immunosuppression therapy may provide some sort of protection for severe clinical complications of COVID‐19. The interaction between immunosuppression and new antiviral drugs in the treatment of transplanted patients contracting COVID‐19 has not yet been fully investigated. Moreover, data regarding the optimal management of these patients are still very limited. We report a case of the successful recovery from severe COVID‐19 of a kidney‐transplanted patient treated with hydroxychloroquine, lopinavir/ritonavir, steroid, and tocilizumab.

Details

Language :
English
ISSN :
13993062 and 13982273
Database :
OpenAIRE
Journal :
Transplant Infectious Disease
Accession number :
edsair.doi.dedup.....79588ba3e6d5c3d818e742c467ce2a7f
Full Text :
https://doi.org/10.1111/tid.13334