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Pregnancy increases the risk of mortality in Wet Nile virus-infected mice
- Source :
- Repositorio de Resultados de Investigación del INIA, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria INIA, INIA: Repositorio de Resultados de Investigación del INIA
- Publication Year :
- 2007
- Publisher :
- Microbiology Society, 2007.
-
Abstract
- West Nile fever outbreaks in the USA have caused over 700 human deaths, primarily due to neurological disease. The usual transmission route of West Nile virus (WNV) involves mosquito bites; however, alternative routes, including intrauterine infection, have also been reported. Here, the pathogenicity of WNV in mice during gestation has been investigated. An extremely high mortality rate was observed in pregnant mice (98 %, 60/61) compared with non-pregnant mice (52 %, 28/53; P
- Subjects :
- viruses
Antibodies, Viral
Virus
Mice
Flaviviridae
Pregnancy
Virology
medicine
Animals
Pregnancy Complications, Infectious
reproductive and urinary physiology
Mice, Inbred BALB C
biology
Transmission (medicine)
Mortality rate
Brain
virus diseases
Outbreak
biology.organism_classification
medicine.disease
nervous system diseases
Flavivirus
Immunology
RNA, Viral
Gestation
Female
West Nile virus
West Nile Fever
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- Repositorio de Resultados de Investigación del INIA, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria INIA, INIA: Repositorio de Resultados de Investigación del INIA
- Accession number :
- edsair.doi.dedup.....7944bf0c866cd381f15a04a2edeaea1f