Possible role of low dose dexamethasone administration in listeria monocytogenes meningoencephalitis: A case series

Subjects

Subjects :

five cases of L. monocytogenes meningitis/meningoencephalitis affecting two previously healthy immunocompetent and three immunocompromised adult patients treated with ampicillin plus gentamicin are reported. In addition
General Neuroscience
non-sporulating
meningoencephalitis
four of them made a full recovery. Additionally
which typically affects immunocompromised patients
General Medicine
all the patients described in this report received a low dose of intravenous dexamethasone
highlighting the value of dexamethasone administration as part of the therapy
General Biochemistry, Genetics and Molecular Biology
Listeria (L.) monocytogenes is a gram-positive
facultatively anaerobic bacillus transmitted to humans through ingestion of contaminated foods. Listeriosis represents the third most common cause of death from foodborne illness
a literature search was performed to better explain the appropriate clinical and therapeutic management approaches for these patients
and sepsis are the most challenging to deal with. Here
and neonates. It causes several clinical syndromes
General Pharmacology, Toxicology and Pharmaceutics
the elderly
especially for patients affected by an invasive disease
of which meningitis
Listeria (L.) monocytogenes is a gram-positive, non-sporulating, facultatively anaerobic bacillus transmitted to humans through ingestion of contaminated foods. Listeriosis represents the third most common cause of death from foodborne illness, with a mortality rate of 20-30%, especially for patients affected by an invasive disease, which typically affects immunocompromised patients, pregnant women, the elderly, and neonates. It causes several clinical syndromes, of which meningitis, meningoencephalitis, and sepsis are the most challenging to deal with. Here, five cases of L. monocytogenes meningitis/meningoencephalitis affecting two previously healthy immunocompetent and three immunocompromised adult patients treated with ampicillin plus gentamicin are reported. In addition, all the patients described in this report received a low dose of intravenous dexamethasone
four of them made a full recovery. Additionally, a literature search was performed to better explain the appropriate clinical and therapeutic management approaches for these patients, highlighting the value of dexamethasone administration as part of the therapy
pregnant women
with a mortality rate of 20-30%

Details

Language :

English

Database :

OpenAIRE

Accession number :

edsair.doi.dedup.....78d891a22f5cef8bb43f8629c22c38b9