Short-Term Effects of Air Pollution on Heart Rate Variability in Senior Adults in Steubenville, Ohio

We examined the association between ambient air pollution levels and heart rate variability (HRV) in a panel study of 32 subjects.We used linear mixed models to analyze the effects of fine particles (PM2.5), sulfate (SO4), elemental carbon (EC), and gases on log-transformed standard deviation of normal RR intervals (SDNN), mean square of differences between adjacent RR intervals (r-MSSD), and high- and low-frequency power (HF, LF).An interquartile range (IQR) increase of 5.1 mug/m in SO4 on the previous day was associated with a decrease of -3.3% SDNN (95% confidence = -6.0% to -0.5%), -5.6% r-MSSD (-10.7% to -0.2%), and -10.3% HF (-19.5% to -0.1%). Associations with total PM2.5 were similar. HRV was not associated with EC, NO2, SO2, or O3.In addition to traffic-related particles, elevated levels of sulfate particles may also adversely affect autonomic function.