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Quasi-Complete Response of Classic Kaposi’s Sarcoma Treated with Weekly Paclitaxel
- Source :
- Case Reports in Oncological Medicine, Vol 2013 (2013), Case Reports in Oncological Medicine
- Publication Year :
- 2013
- Publisher :
- Hindawi Limited, 2013.
-
Abstract
- Classic Kaposi’s sarcoma (CKS) is a subtype that traditionally occurs in elderly HIV-negative males of Mediterranean origin. Patients with CKS characteristically present with skin lesions in the distal extremities. Involvement of the viscera is uncommon but may occur in the late stages of the disease. Patients with extensive KS can be treated with systemic chemotherapy. A number of drugs approved for treatment of AIDS-associated KS, especially Paclitaxel, have activity against CKS after failure of prior therapy. We report a patient treated with weekly Paclitaxel, as initial chemotherapy, for CKS presenting with multiple visceral involvement and having a contraindication for Bleomycin. The patient had quasi-complete response after three months of chemotherapy suggesting that weekly Paclitaxel might be effective as a first-line therapy for classical type KS with visceral involvement.
- Subjects :
- Oncology
Chemotherapy
medicine.medical_specialty
Pathology
business.industry
medicine.medical_treatment
Weekly paclitaxel
Case Report
Disease
Bleomycin
medicine.disease
lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
lcsh:RC254-282
chemistry.chemical_compound
Prior Therapy
Paclitaxel
chemistry
Internal medicine
medicine
Sarcoma
business
Contraindication
Subjects
Details
- Language :
- English
- ISSN :
- 20906714 and 20906706
- Volume :
- 2013
- Database :
- OpenAIRE
- Journal :
- Case Reports in Oncological Medicine
- Accession number :
- edsair.doi.dedup.....78bef61884f3847a211d29315c6c73d6