Senile changes of crystalline lens: effects on the delayed latency of pattern visually evoked potentials in phakic and pseudophakic eyes

We recorded visually evoked cortical potentials to pattern stimuli (PVECPs) in 22 patients who received a posterior chamber intraocular lens implant. The mean latency of the P100 obtained from patients was not significantly different from that of age-matched normal phakic subjects. Furthermore, we found that both groups showed a similar increased delay of the P100 latency with age. The results of this study indicated that the senile opacity of the crystalline lens does not contribute to changes of PVECPs with age. These alterations may be due to senile changes of the neural pathway.