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Association Between Contact Lens Discomfort and Pre-lens Tear Film Kinetics
- Source :
- Optometry and Vision Science. 93:881-891
- Publication Year :
- 2016
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 2016.
-
Abstract
- PURPOSE The relationship between contact lens wettability and comfort has been extensively evaluated; however, a direct correlation between the characteristics of the pre-lens tear film and the symptoms associated with contact lens discomfort has yet to be established. In addition, there is relatively limited knowledge relating to the entire tear film kinetics during the inter-blink period in contact lens wearers. The purpose of this analysis was to identify the characteristics of the pre-lens tear film kinetics that may be associated with the symptoms of contact lens discomfort. METHODS The study population comprised 202 soft (hydrogel and silicone hydrogel) contact lens wearers attending pre-screening visits at the OTG-i research clinic. All participants completed the Ocular Surface Disease Index (OSDI) questionnaire and the tear film was quantified via post hoc, masked analysis of high definition digital Tearscope videos recorded at the visit. The tear film kinetics of the least symptomatic wearers (OSDI lowest quintile scores, n = 45) were compared to the tear film kinetics of the most symptomatic wearers (OSDI highest quintile scores, n = 43). The hypothesis tested was that the tear film kinetics of asymptomatic wearers were better than tear film kinetics of symptomatic wearers. RESULTS The distribution of lens types worn was as follows: Daily Disposable 46.5%, 1-Month Replacement 39.6%, and 2-Week Replacement 13.6%. 48.2% of lenses were silicone hydrogel and 51.8% hydrogel. Symptomatic wearers had a shorter break-up time (4.7 s vs. 6.0 s; p = 0.003), lesser surface coverage by the tear film during the interblink period (95.1% vs. 98.5%; p < 0.001) and greater surface exposure at the time of the blink (9.4% vs. 3.9%; p = 0.001). CONCLUSIONS The current study demonstrated that the tear film kinetics of asymptomatic and symptomatic contact lens wearers were different, the findings supporting the hypothesis of poorer tear film kinetics for symptomatic than asymptomatic wearers in a general contact lens wearing population.
- Subjects :
- Adult
Male
medicine.medical_specialty
Adolescent
Post hoc
Population
Asymptomatic
law.invention
Young Adult
03 medical and health sciences
0302 clinical medicine
law
Ophthalmology
medicine
Humans
Ocular Surface Disease Index
education
Retrospective Studies
education.field_of_study
Blinking
business.industry
Middle Aged
Contact Lenses, Hydrophilic
Prognosis
Refractive Errors
Lens (optics)
Contact lens
Kinetics
Patient Satisfaction
Tears
Wettability
030221 ophthalmology & optometry
High definition
Female
Daily disposable
medicine.symptom
business
030217 neurology & neurosurgery
Follow-Up Studies
Optometry
Subjects
Details
- ISSN :
- 15389235 and 10405488
- Volume :
- 93
- Database :
- OpenAIRE
- Journal :
- Optometry and Vision Science
- Accession number :
- edsair.doi.dedup.....7859ceb22f9f8d36d13d3dec91c75238
- Full Text :
- https://doi.org/10.1097/opx.0000000000000866