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The Utility and Efficacy of Laparoscopic Radical Cystectomy in Patients with Muscle-Invasive Bladder Cancer at a Single Institution
- Source :
- Urologia Internationalis. 104:573-579
- Publication Year :
- 2020
- Publisher :
- S. Karger AG, 2020.
-
Abstract
- Background: The aim of this study was to compare the surgical and oncological outcomes and complications of laparoscopic radical cystectomy (LRC) to those of open radical cystectomy (ORC) in patients with muscle-invasive bladder cancer (MIBC). Methods: Our study focused on patients with histologically confirmed stage T2–T4a urothelial carcinoma of the bladder without distant metastases, who underwent LRC (LRC group) or ORC (ORC group). The primary endpoints in this study were the overall survival (OS) and recurrence-free survival (RFS) rates. Results: In this study, 59 patients, 17 underwent LRC and 42 underwent ORC, were enrolled. The 2-year OS rate was 100% in the LRC group and 88.0% in the ORC group (p = 0.85). The 2-year RFS rate was 63.5% in the LRC group and 69.5% in the ORC group (p = 0.321). On multivariate analysis, the histological type, positive lymph node, and positive resection margin were significantly associated with the OS rates. Conclusions: This study suggested that LRC may achieve similar oncological outcomes and fewer perioperative complications and less blood loss compared to ORC. Therefore, LRC should be considered as one of the treatment options for patients with MIBC.
- Subjects :
- Male
medicine.medical_specialty
Urology
medicine.medical_treatment
Cystectomy
medicine
Humans
Neoplasm Invasiveness
In patient
Single institution
Stage (cooking)
Aged
Retrospective Studies
Carcinoma, Transitional Cell
Bladder cancer
business.industry
Muscle invasive
Perioperative
Middle Aged
medicine.disease
Survival Rate
Treatment Outcome
Urinary Bladder Neoplasms
Resection margin
Female
Laparoscopy
business
Subjects
Details
- ISSN :
- 14230399 and 00421138
- Volume :
- 104
- Database :
- OpenAIRE
- Journal :
- Urologia Internationalis
- Accession number :
- edsair.doi.dedup.....7851683c351c1147831c61a2170fbde2