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Gender Issues in the Pharmacotherapy of Opioid-Addicted Women: Buprenorphine
- Source :
- Journal of Addictive Diseases. 29:217-230
- Publication Year :
- 2010
- Publisher :
- Informa UK Limited, 2010.
-
Abstract
- Gender, a biological determinant of mental health and illness, plays a critical role in determining patients’ susceptibility, exposure to mental health risks, and related outcomes. Regarding sex differences in the epidemiology of opioid dependence, one third of the patients are women of childbearing age. Women have an earlier age of initiation of substance use and a more rapid progression to drug involvement and dependence than men. Generally few studies exist which focus on the special needs of women in opioid maintenance therapy. The aim of this paper is to provide an overview of treatment options for opioid-dependent women, with a special focus on buprenorphine, and to look at recent findings related to other factors that should be taken into consideration in optimizing the treatment of opioid-dependent women. Issues addressed include the role of gender in the choice of medication assisted treatment, sex differences in pharmacodynamics and pharmacokinetics of buprenorphine drug interactions, cardiac interactions, induction of buprenorphine in pregnant patients, the neonatal abstinence syndrome and breastfeeding. This paper aims to heighten the awareness for the need to take gender into consideration when making treatment decisions in an effort to optimize services and enhance the quality of life of women suffering from substance abuse.
- Subjects :
- medicine.medical_specialty
Narcotic Antagonists
media_common.quotation_subject
Breastfeeding
Medicine (miscellaneous)
Special needs
Article
Sex Factors
Pharmacotherapy
Pregnancy
Epidemiology
medicine
Humans
Women
Psychiatry
Randomized Controlled Trials as Topic
media_common
business.industry
Infant, Newborn
Pregnancy Outcome
General Medicine
Abstinence
Opioid-Related Disorders
medicine.disease
Mental health
Buprenorphine
Pregnancy Complications
Substance abuse
Psychiatry and Mental health
Clinical Psychology
Treatment Outcome
Female
business
Neonatal Abstinence Syndrome
medicine.drug
Subjects
Details
- ISSN :
- 15450848 and 10550887
- Volume :
- 29
- Database :
- OpenAIRE
- Journal :
- Journal of Addictive Diseases
- Accession number :
- edsair.doi.dedup.....7837625a3f0f87d81ed246ae67f2e972