Additional file 1 of HERC2 promotes inflammation-driven cancer stemness and immune evasion in hepatocellular carcinoma by activating STAT3 pathway

Additional file 1: Supplementary Fig. S1. IL-6-induced HERC2 expression is associated with HCC progression. Supplementary Fig. S2. HERC2 promoted the immune evasion of HCC cells. Supplementary Fig. S3. HERC2-positive tumor cells displayed higher STAT3-targeted gene expression. Supplementary Fig. S4. HERC2 promoted malignancy of HCC cells via STAT3 signaling. Supplementary Fig. S5. HERC2 enhanced stemness and immune evasion of HCC cells through STAT3 signaling. Supplementary Fig. S6. HERC2 promoted malignancy of HCC cells through PTP1B. Supplementary Fig. S7. HERC2 promoted stemness and immune evasion of HCC cells through PTP1B. Supplementary Fig. S8. Establishment of hepatocyte-specific HERC2 knockout mice.