Additional file 6: of Purification of nanogram-range immunoprecipitated DNA in ChIP-seq application

Measuring global ChIP enrichment by FRiP (fraction of reads in peaks). The score of FRiP (fraction of reads in peaks) was calculated by the previously published method [3]. FRiP scores for H3K4me3 and H3K27me3 ChIP-seq are visualized from the ENCODE reference (ENB and ENw) and the corresponding datasets obtained either with standard protocol for the lab (St) or by using different purification reagents as identified in Fig. 1. (PDF 94Â kb)