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Phytosterols: Nutritional Health Players in the Management of Obesity and Its Related Disorders
- Source :
- Antioxidants, Vol 9, Iss 1266, p 1266 (2020), Antioxidants
- Publication Year :
- 2020
- Publisher :
- MDPI AG, 2020.
-
Abstract
- Obesity and its related disorders, such as diabetes and cardiovascular risk, represent an emerging global health issue. Even though genetic factors seem to be the primary actors in the development and progression of these diseases, dietary choices also appear to be of crucial importance. A healthy diet combined with physical activity have been shown to ameliorate glycaemic levels and insulin sensitivity, reduce body weight and the risk of chronic diseases, and contribute to an overall improvement in quality of life. Among nutrients, phytosterols have become the focus of growing attention as novel functional foods in the management of metabolic disorders. Phytosterols are natural plant compounds belonging to the triterpene family and are structurally similar to cholesterol. They are known for their cholesterol-lowering effects, anti-inflammatory and antioxidant properties, and the benefits they offer to the immune system. The present review aims to provide an overview of these bioactive compounds and their therapeutic potential in the fields of obesity and metabolic disorders, with special attention given to oxidative stress, inflammatory status, and gut dysbiosis, all common features of the aforementioned diseases.
- Subjects :
- 0301 basic medicine
obesity
Physiology
Clinical Biochemistry
phytosterols
030209 endocrinology & metabolism
Review
Bioinformatics
Biochemistry
Management of obesity
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
Quality of life (healthcare)
Immune system
Diabetes mellitus
Global health
microbiota
Medicine
metabolic disorders
Molecular Biology
bioactive compounds
business.industry
Cholesterol
lcsh:RM1-950
Insulin sensitivity
Cell Biology
medicine.disease
Obesity
antioxidant properties
030104 developmental biology
lcsh:Therapeutics. Pharmacology
chemistry
anti-inflammatory properties
business
Subjects
Details
- Language :
- English
- ISSN :
- 20763921
- Volume :
- 9
- Issue :
- 1266
- Database :
- OpenAIRE
- Journal :
- Antioxidants
- Accession number :
- edsair.doi.dedup.....77ca12669ea906a85aac4cef738c4887