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A cross-sectional study investigating frequency and features of definitely diagnosed diabetic painful polyneuropathy
- Publication Year :
- 2018
- Publisher :
- NLM (Medline), 2018.
-
Abstract
- This cross-sectional multicentre study aimed at investigating frequency and features of painful diabetic polyneuropathyWe consecutively enrolled 816 patients attending hospital diabetic outpatient clinics. We first definitely diagnosed diabetic polyneuropathy and pure small-fibre polyneuropathy using clinical examination, nerve conduction study, and skin biopsy or quantitative sensory testing. Adhering to widely agreed criteria, we then identified neuropathic pain and diagnosed painful polyneuropathy using a combined approach of clinical examination and diagnostic testsOut of the 816 patients, 36% had a diabetic polyneuropathy associated with male gender, age and diabetes severity; 2.5% of patients had a pure small-fibre polyneuropathy, unrelated to demographic variables and diabetes severity. Of the 816 patients, 115 (13%) suffered from a painful polyneuropathy, with female gender as the only risk factor for suffering from painful polyneuropathyIn this large study, providing a definite diagnosis of diabetic polyneuropathy and pure small-fibre polyneuropathy, we show the frequency of painful polyneuropathy, and demonstrate that this difficult to treat complication is more common in women than in men.
- Subjects :
- Male
Pediatrics
Diabetic neuropathy
Biopsy
Neural Conduction
Neuropathic pain
Settore MED/13 - Endocrinologia
0302 clinical medicine
Diabetic Neuropathies
Outpatient clinic
Prospective Studies
Prospective cohort study
Pain Measurement
Skin
Aged, 80 and over
Neurologic Examination
Small-fibre neuropathy
medicine.diagnostic_test
small fibre neuropathy
Diabetes
Middle Aged
Neurology
Nerve conduction study
Settore MED/26 - Neurologia
Polyneuropathy
Adult
medicine.medical_specialty
neuropathic pain
peripheral neuropathy
diabetes
Small Fiber Neuropathy
030209 endocrinology & metabolism
Physical examination
Young Adult
03 medical and health sciences
Diabetes mellitus
medicine
Humans
Aged
business.industry
medicine.disease
Neurology (clinical)
Anesthesiology and Pain Medicine
Cross-Sectional Studies
diabete
Skin biopsy
Neuralgia
diabetic neuropathy, neuropathic pain, small fibre neuropathy
Complication
business
030217 neurology & neurosurgery
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....772ee3456fef2dc0b32026950009463d