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Mixed Etiology COVID-19 Associated Pulmonary Aspergillosis (CAPA)—A Case Report and Brief Review of the Literature

Authors :
Carmen Costache
Razvan Marian Mihaila
Dan Alexandru Toc
Sandor Botond Buksa
Roxana Mihaela Chiorescu
Ioana Alina Colosi
Alexandru Botan
Source :
Journal of Fungi, Vol 7, Iss 877, p 877 (2021), Journal of Fungi
Publication Year :
2021
Publisher :
MDPI AG, 2021.

Abstract

The SARS-CoV-2 pandemic has proved to be a significant risk addition for invasive infections with Aspergillus. Even though there are plenty of data about the COVID-19-associated pulmonary aspergillosis (CAPA), especially involving Aspergillus fumigatus, recent studies are presenting cases of CAPA involving more than one species of Aspergillus. We report the first case of a SARS-CoV-2 patient associating co-infection with, most likely, Aspergillus section Fumigati and Aspergillus section Flavi from Romania, and we review the existing medical literature in order to shed light upon mixed etiology cases of CAPA. Since mortality remains high in these cases, there is an acute need for more information about the interaction between SARS-CoV-2 and Aspergillus spp., and the therapies for CAPA. The emerging number of cases and the high mortality rate must be considered an incentive for future research.

Details

Language :
English
Volume :
7
Issue :
877
Database :
OpenAIRE
Journal :
Journal of Fungi
Accession number :
edsair.doi.dedup.....76fb2ad20f7b96f2c832967b7ded0c1d