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A five‐mRNA signature associated with post‐translational modifications can better predict recurrence and survival in cervical cancer

Authors :
Lin Wang
Lin Zhao
Longyang Jiang
Qiang Zhang
Jia Bi
Lan Zhao
Qiutong Guan
Minjie Wei
Xueping Li
Mingyi Ju
Qian Wei
Aoshuang Qi
Source :
Journal of Cellular and Molecular Medicine
Publication Year :
2020
Publisher :
Wiley, 2020.

Abstract

High mortality of patients with cervical cancer (CC) stresses the imperative of prognostic biomarkers for CC patients. Additionally, the vital status of post‐translational modifications (PTMs) in the progression of cancers has been reported by numerous researches. Therefore, the purpose of this research was to dig a prognostic signature correlated with PTMs for CC. We built a five‐mRNA (GALNTL6, ARSE, DPAGT1, GANAB and FURIN) prognostic signature associated with PTMs to predict both disease‐free survival (DFS) (hazard ratio [HR] = 3.967, 95% CI = 1.985‐7.927; P

Details

ISSN :
15824934 and 15821838
Volume :
24
Database :
OpenAIRE
Journal :
Journal of Cellular and Molecular Medicine
Accession number :
edsair.doi.dedup.....76e3befb2d8ba90cf6fc746b21a723e6
Full Text :
https://doi.org/10.1111/jcmm.15270