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Lipid selection in the assembly of the phospholipid bilayer membrane of the lipid-containing bacteriophage PR4
- Source :
- Virology. 198(1)
- Publication Year :
- 1994
-
Abstract
- Phage PR4 contains a lipid bilayer within the phage protein capsid. The phospholipids of the bilayer are derived from those of the host. We report that phage morphogenesis selects against the unusually bulky phospholipids synthesized by Escherichia coli grown in the presence of various sugar alcohols. These data indicate that assembly of the PR4 lipid bilayer is a selective process rather than the bulk appropriation of host membrane lipids. We also demonstrate that phage PR4 morphogenesis is compatible with the incorporation of several abnormal lipids, monoacylglycerol, diacylglycerol, and phosphatidylinositol into the phage particle.
- Subjects :
- biology
viruses
Membrane lipids
Bilayer
Phosphatidylethanolamines
Lipid Bilayers
Tectivirus
Phospholipid
Biological membrane
Phosphatidylglycerols
biology.organism_classification
Coliphages
Bacteriophage
chemistry.chemical_compound
Biochemistry
chemistry
Virology
lipids (amino acids, peptides, and proteins)
Mannitol
Lipid bilayer
Salmonella Phages
Phospholipids
Diacylglycerol kinase
Subjects
Details
- ISSN :
- 00426822
- Volume :
- 198
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Virology
- Accession number :
- edsair.doi.dedup.....76de58f2e87261d3b18aba48ba32bb48