Imaging Calcium Concentration Dynamics in Small Neuronal Compartments

Authors :: Karel Svoboda
Thomas G. Oertner
Volker Scheuss
Esther A. Nimchinsky
Ryohei Yasuda
Thomas A. Pologruto
Bernardo L. Sabatini
Source :: Science's STKE. 2004
Publication Year :: 2004
Publisher :: American Association for the Advancement of Science (AAAS), 2004.
Abstract: Calcium and its regulation play central roles diverse physiologic processes. Quantification of calcium concentrations ([Ca 2+ ]) in small neuronal compartments is crucial to understanding Ca 2+ -dependent signaling. Here, we describe techniques that are optimized for 2-photon imaging of [Ca 2+ ] dynamics in small compartments such as dendrites and dendritic spines.

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