Risk factors for early treatment discontinuation in patients with obsessive-compulsive disorder

Authors :: Roseli G. Shavitt
Sonia Borcato
Juliana Belo Diniz
Euripedes Constantino Miguel
Dante Marino Malavazzi
Victor Fossaluza
Cristina Belotto-Silva
Izabel Pimentel
Source :: Clinics, Vol 66, Iss 3, Pp 387-393 (2011), Clinics; v. 66 n. 3 (2011); 387-393, Clinics; Vol. 66 Núm. 3 (2011); 387-393, Clinics; Vol. 66 No. 3 (2011); 387-393, Clinics, Universidade de São Paulo (USP), instacron:USP, Clinics, Volume: 66, Issue: 3, Pages: 387-393, Published: 2011
Publication Year :: 2011
Publisher :: Faculdade de Medicina / USP, 2011.
Abstract: INTRODUCTION: In obsessive-compulsive disorder, early treatment discontinuation can hamper the effectiveness of first-line treatments. OBJECTIVE: This study aimed to investigate the clinical correlates of early treatment discontinuation among obsessive-compulsive disorder patients. METHODS: A group of patients who stopped taking selective serotonin reuptake inhibitors (SSRIs) or stopped participating in cognitive behavioral therapy before completion of the first twelve weeks (total n = 41; n = 16 for cognitive behavioral therapy and n = 25 for SSRIs) were compared with a paired sample of compliant patients (n = 41). Demographic and clinical characteristics were obtained at baseline using structured clinical interviews. Chi-square and Mann-Whitney tests were used when indicated. Variables presenting a p value

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