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Standardized Postnatal Management of Infants with Congenital Diaphragmatic Hernia in Europe: The CDH EURO Consortium Consensus - 2015 Update
- Source :
- Neonatology, 110, 66-74, Neonatology, 110, 1, pp. 66-74, Neonatology, 110(1), 66-74. Karger, Snoek, K G, Reiss, I K M, Greenough, A, Capolupo, I, Urlesberger, B, Wessel, L, Storme, L, Deprest, J, Schaible, T, Van Heijst, A, Tibboel, D, Allegaert, K, Debeer, A, Keijzer, R, Benachi, A, Tissieres, P, Kipfmueller, F, Schaible, T, Breatnach, C, Patel, N, Leva, E, Ciralli, F, Bagolan, P, Dotta, A, Morini, F, Di Pede, A, Emblem, R, Ertesvag, K, Migdal, M, Piotrowski, A, Frenckner, B, Mesas, C, Elorza, D, Martinez, L, Scharbatke, H, Cohen-Overbeek, T, Eggink, A J, Kraemer, U S, Tibboel, D, Wijnen, R M H, Deprest, J, De Coppi, P, Eaton, S & Davenport, M 2016, ' Standardized postnatal management of infants with congenital diaphragmatic hernia in Europe : The CDH EURO Consortium Consensus-2015 Update ', Neonatology, vol. 110, no. 1, pp. 66-74 . https://doi.org/10.1159/000444210
- Publication Year :
- 2016
-
Abstract
- Contains fulltext : 168576.pdf (Publisher’s version ) (Open Access) In 2010, the congenital diaphragmatic hernia (CDH) EURO Consortium published a standardized neonatal treatment protocol. Five years later, the number of participating centers has been raised from 13 to 22. In this article the relevant literature is updated, and consensus has been reached between the members of the CDH EURO Consortium. Key updated recommendations are: (1) planned delivery after a gestational age of 39 weeks in a high-volume tertiary center; (2) neuromuscular blocking agents to be avoided during initial treatment in the delivery room; (3) adapt treatment to reach a preductal saturation of between 80 and 95% and postductal saturation >70%; (4) target PaCO2 to be between 50 and 70 mm Hg; (5) conventional mechanical ventilation to be the optimal initial ventilation strategy, and (6) intravenous sildenafil to be considered in CDH patients with severe pulmonary hypertension. This article represents the current opinion of all consortium members in Europe for the optimal neonatal treatment of CDH.
- Subjects :
- Postnatal Care
medicine.medical_specialty
Pediatrics
Consensus
Hypertension, Pulmonary
Standardized treatment
MEDLINE
Congenital diaphragmatic hernia
Sildenafil Citrate
law.invention
Randomized controlled trial
Clinical Protocols
law
medicine
Humans
Hernia
Intensive care medicine
Expert Testimony
Monitoring, Physiologic
business.industry
High mortality
Infant, Newborn
Infant
Postnatal treatment
Patient data
medicine.disease
Respiration, Artificial
Europe
Reconstructive and regenerative medicine Radboud Institute for Molecular Life Sciences [Radboudumc 10]
Settore MED/20
Pediatrics, Perinatology and Child Health
Practice Guidelines as Topic
business
Hernias, Diaphragmatic, Congenital
Developmental Biology
Subjects
Details
- ISSN :
- 16617800
- Database :
- OpenAIRE
- Journal :
- Neonatology, 110, 66-74, Neonatology, 110, 1, pp. 66-74, Neonatology, 110(1), 66-74. Karger, Snoek, K G, Reiss, I K M, Greenough, A, Capolupo, I, Urlesberger, B, Wessel, L, Storme, L, Deprest, J, Schaible, T, Van Heijst, A, Tibboel, D, Allegaert, K, Debeer, A, Keijzer, R, Benachi, A, Tissieres, P, Kipfmueller, F, Schaible, T, Breatnach, C, Patel, N, Leva, E, Ciralli, F, Bagolan, P, Dotta, A, Morini, F, Di Pede, A, Emblem, R, Ertesvag, K, Migdal, M, Piotrowski, A, Frenckner, B, Mesas, C, Elorza, D, Martinez, L, Scharbatke, H, Cohen-Overbeek, T, Eggink, A J, Kraemer, U S, Tibboel, D, Wijnen, R M H, Deprest, J, De Coppi, P, Eaton, S & Davenport, M 2016, ' Standardized postnatal management of infants with congenital diaphragmatic hernia in Europe : The CDH EURO Consortium Consensus-2015 Update ', Neonatology, vol. 110, no. 1, pp. 66-74 . https://doi.org/10.1159/000444210
- Accession number :
- edsair.doi.dedup.....76bd0f3b7b7dd12432722cdc42ceed9c