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Patent foramen ovale and ventricular septal defect closure
- Source :
- Heart. 95:70-82
- Publication Year :
- 2008
- Publisher :
- BMJ, 2008.
-
Abstract
- Despite the growing recognition of the patent foramen ovale (PFO), particularly when associated with an atrial septal aneurysm, as risk factor for several disease manifestations (above all paradoxical embolism), the optimal treatment strategy for symptomatic patients remains controversial. Percutaneous PFO closure is a minimally invasive procedure which can be performed with high success and low morbidity. For secondary prevention of recurrent embolic events, it appears to be clinically at least as effective as oral anticoagulation. Ventricular septal defects (VSDs) are the most common congenital heart defects. Percutaneous VSD closure is more intricate than PFO closure. It is associated with a significant risk of both peri-interventional and mid-term complications. In suitable patients with congenital VSD, device closure may well be the preferred treatment both for muscular or perimembranous VSDs and for residual defects after surgical VSD closure. The risk of complete atrioventricular conduction block remains a concern in the perimembranous group. The history, technique and clinical role of percutaneous PFO and VSD closure are discussed, with emphasis on current problems and future developments.
- Subjects :
- Adult
Heart Septal Defects, Ventricular
congenital, hereditary, and neonatal diseases and abnormalities
medicine.medical_specialty
Percutaneous
Embolism
Foramen secundum
Foramen Ovale, Patent
Persistent fetal circulation
Paradoxical embolism
Internal medicine
medicine
Humans
Angioplasty, Balloon, Coronary
Foramen ovale (heart)
Heart septal defect
business.industry
Equipment Design
Balloon Occlusion
medicine.disease
Surgery
medicine.anatomical_structure
Practice Guidelines as Topic
Cardiology
Patent foramen ovale
Female
Cardiology and Cardiovascular Medicine
business
Echocardiography, Transesophageal
Forecasting
Subjects
Details
- ISSN :
- 13556037
- Volume :
- 95
- Database :
- OpenAIRE
- Journal :
- Heart
- Accession number :
- edsair.doi.dedup.....76a6e0c3df4eb58eee8472ebef4c4627