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Plants derived therapeutic strategies targeting chronic respiratory diseases: Chemical and immunological perspective
- Source :
- Chemico-Biological Interactions
- Publication Year :
- 2020
- Publisher :
- Elsevier BV, 2020.
-
Abstract
- The apparent predicament of the representative chemotherapy for managing respiratory distress calls for an obligatory deliberation for identifying the pharmaceuticals that effectively counter the contemporary intricacies associated with target disease. Multiple, complex regulatory pathways manifest chronic pulmonary disorders, which require chemotherapeutics that produce composite inhibitory effect. The cost effective natural product based molecules hold a high fervor to meet the prospects posed by current respiratory-distress therapy by sparing the tedious drug design and development archetypes, present a robust standing for the possible replacement of the fading practice of poly-pharmacology, and ensure the subversion of a potential disease relapse. This study summarizes the experimental evidences on natural products moieties and their components that illustrates therapeutic efficacy on respiratory disorders.<br />Highlights • Plant derived therapeutics for managing chronic respiratory disorders. • Activity of natural product based molecules on key regulatory pathways of COPD. • Preclinical evidence for the efficacy of natural product moieties. • Clinical significance of plant derived molecules in pulmonary distress.
- Subjects :
- 0301 basic medicine
Drug
medicine.medical_specialty
Coronavirus disease 2019 (COVID-19)
media_common.quotation_subject
Respiratory Tract Diseases
Disease
0601 Biochemistry and Cell Biology
Toxicology
Article
03 medical and health sciences
0302 clinical medicine
Alkaloids
medicine
Animals
Humans
COPD
Molecular Targeted Therapy
Intensive care medicine
Inhibitory effect
media_common
Flavonoids
Natural products
Respiratory distress
business.industry
Plant Extracts
Perspective (graphical)
Respiratory disorders
General Medicine
3. Good health
030104 developmental biology
030220 oncology & carcinogenesis
Chronic Disease
business
DISEASE RELAPSE
Pulmonary disorders
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- Chemico-Biological Interactions
- Accession number :
- edsair.doi.dedup.....7692bab4ccc46cb7eb201d1ddbf2ea01