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Hyperacute Rejection of a Living Unrelated Kidney Graft
- Source :
- Case Reports in Medicine, Vol 2014 (2014), Case Reports in Medicine
- Publication Year :
- 2014
- Publisher :
- Hindawi Limited, 2014.
-
Abstract
- We present a case report of a 59-year-old man, who received a blood group identical living unrelated kidney graft. This was his second kidney transplantation. Pretransplant T-cell crossmatch resulted negative. B-cell crossmatch, which is not considered a strict contraindication for transplantation, resulted positive. During surgery no abnormalities occurred. Four hours after the transplantation diuresis suddenly decreased. In an immediately performed relaparotomy the transplanted kidney showed signs of hyperacute rejection and had to be removed. Pathological examination was consistent with hyperacute rejection. Depositions of IgM or IgG antibodies were not present in pathologic evaluation of the rejected kidney, suggesting that no irregular endothelial specific antibodies had been involved in the rejection. We recommend examining more closely recipients of second allografts, considering not only a positive T-cell crossmatch but also a positive B-cell crossmatch as exclusion criteria for transplantation.
- Subjects :
- medicine.medical_specialty
Kidney
biology
business.industry
lcsh:R
Urology
Diuresis
lcsh:Medicine
Case Report
General Medicine
medicine.disease
Surgery
Transplantation
Specific antibody
medicine.anatomical_structure
surgical procedures, operative
biology.protein
Medicine
Antibody
business
Contraindication
Pathological
Kidney transplantation
Subjects
Details
- Language :
- English
- ISSN :
- 16879635 and 16879627
- Volume :
- 2014
- Database :
- OpenAIRE
- Journal :
- Case Reports in Medicine
- Accession number :
- edsair.doi.dedup.....7682ca5e3f9a85775aa506e5bae1c9c5