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Selective detection of cysteine/cystine using silver nanoparticles
- Source :
- Tetrahedron Letters. 54:427-430
- Publication Year :
- 2013
- Publisher :
- Elsevier BV, 2013.
-
Abstract
- The selective detection of cysteine and cystine amino acids over other standard amino acids was possible with the naked eye using silver nanoparticles (AgNPs) in a simple procedure at room temperature. The change in color and the aggregation of NPs were studied using UV–vis spectroscopy and transmission electron microscopy, respectively. It was observed that when the derivative and substructures of cysteine were employed as analytes the detection was possible only when there is free SH or S–S group present in the analytes. The method was extended to a dipeptide ‘cys-gly’ as a model peptide where the detection was successful due to the presence of SH moiety.
- Subjects :
- silver nanop amino acid analysis
Inorganic chemistry
ultraviolet spectroscopy
Cystine
Peptide
Biochemistry
Silver nanoparticle
chemistry.chemical_compound
transmission electron microscopy
Drug Discovery
Moiety
cysteine
cystine
chemistry.chemical_classification
cysteine derivative
Dipeptide
Organic Chemistry
Combinatorial chemistry
peptide
color
Amino acid
chemistry
chemical structure
Naked eye
room temperature
Cysteine
Subjects
Details
- ISSN :
- 00404039
- Volume :
- 54
- Database :
- OpenAIRE
- Journal :
- Tetrahedron Letters
- Accession number :
- edsair.doi.dedup.....766ba15c7110ebb8fb7d8580e990e155