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Ventricular Assist Device Implantation and Bariatric Surgery: A Route to Transplantation in Morbidly Obese Patients with End-Stage Heart Failure
- Source :
- ASAIO Journal. 67:163-168
- Publication Year :
- 2020
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 2020.
-
Abstract
- We reviewed our experience of morbidly obese patients with end-stage heart failure that underwent left ventricular assist device (LVAD) implantation. From January 1, 2008 to January 1, 2018, 240 adult LVADs were implanted at our center. We reviewed the cases of patients presenting with end-stage heart failure and morbid obesity (preoperative body mass index [BMI] ≥ 35 kg/m2) who underwent LVAD-alone, and compared that to a group that underwent LVAD and bariatric surgery (laparoscopic sleeve gastrectomy [LSG]) as a means for weight reduction. Demographic characteristics, perioperative details, BMI, and status of transplant candidacy were recorded. Statistical analysis was performed (SPSS version 25) with χ2 analysis, Kaplan-Meier survival analysis, regression analysis, and Student's t-test. Twenty-nine patients met criteria and underwent LVAD implantation. Fifteen patients underwent LVAD-alone. Fourteen patients underwent LVAD + LSG. Both groups showed good survival outcomes, LVAD-alone (88.9 ± 5.9 months) versus LVAD +LSG (96.1 ± 12.4 months) but were not significantly different. However, we did note that more patients in the LVAD + LSG group were bridged to heart transplantation (p < 0.001). LVAD-alone and/or LVAD + LSG are both technically feasible and effective treatment options for the long-term survival of morbidly obese patients with end-stage heart failure. Combining LVAD + LSG can help bridge patients to heart transplantation.
- Subjects :
- Adult
Male
medicine.medical_specialty
medicine.medical_treatment
Biomedical Engineering
Biophysics
Bariatric Surgery
Bioengineering
030204 cardiovascular system & hematology
Body Mass Index
Biomaterials
03 medical and health sciences
0302 clinical medicine
Weight loss
Weight Loss
medicine
Humans
Survival analysis
Retrospective Studies
Heart Failure
Heart transplantation
business.industry
General Medicine
Perioperative
Middle Aged
equipment and supplies
medicine.disease
Combined Modality Therapy
Obesity, Morbid
Surgery
Transplantation
Treatment Outcome
030228 respiratory system
Heart failure
Ventricular assist device
Heart Transplantation
Female
Heart-Assist Devices
medicine.symptom
business
Body mass index
Subjects
Details
- ISSN :
- 10582916
- Volume :
- 67
- Database :
- OpenAIRE
- Journal :
- ASAIO Journal
- Accession number :
- edsair.doi.dedup.....764cf9463f1e48a3735ab87bfb651abc
- Full Text :
- https://doi.org/10.1097/mat.0000000000001212