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Expression of Adiponectin and its Receptors in the Porcine Hypothalamus During the Oestrous Cycle

Authors :
Anna Maleszka
Marta Kiezun
Nina Smolinska
Tadeusz Kaminski
Joanna Czerwińska
Karol Szeszko
Anna Nitkiewicz
Kamil Dobrzyn
Source :
Reproduction in Domestic Animals. 49:378-386
Publication Year :
2014
Publisher :
Wiley, 2014.

Abstract

Adiponectin is a hormonal link between obesity and reproduction, and its actions are mediated by two types of receptors: adiponectin receptor 1 (AdipoR1) and adiponectin receptor 2 (AdipoR2). This study compares the expression levels of adiponectin and adiponectin receptor mRNAs and proteins in selected areas of the porcine hypothalamus responsible for GnRH production and secretion: the mediobasal hypothalamus (MBH), pre-optic area (POA) and stalk median eminence (SME). The tissue samples were harvested on days 2-3, 10-12, 14-16 and 17-19 of the oestrous cycle. Adiponectin mRNA expression in MBH was significantly lower on days 14-16, whereas in SME, the most pronounced gene expression was found on days 2-3 of the cycle (p

Details

ISSN :
09366768
Volume :
49
Database :
OpenAIRE
Journal :
Reproduction in Domestic Animals
Accession number :
edsair.doi.dedup.....7620f5d9f6d0addc1e4f650a7f23bbea
Full Text :
https://doi.org/10.1111/rda.12282