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Expression of Adiponectin and its Receptors in the Porcine Hypothalamus During the Oestrous Cycle
- Source :
- Reproduction in Domestic Animals. 49:378-386
- Publication Year :
- 2014
- Publisher :
- Wiley, 2014.
-
Abstract
- Adiponectin is a hormonal link between obesity and reproduction, and its actions are mediated by two types of receptors: adiponectin receptor 1 (AdipoR1) and adiponectin receptor 2 (AdipoR2). This study compares the expression levels of adiponectin and adiponectin receptor mRNAs and proteins in selected areas of the porcine hypothalamus responsible for GnRH production and secretion: the mediobasal hypothalamus (MBH), pre-optic area (POA) and stalk median eminence (SME). The tissue samples were harvested on days 2-3, 10-12, 14-16 and 17-19 of the oestrous cycle. Adiponectin mRNA expression in MBH was significantly lower on days 14-16, whereas in SME, the most pronounced gene expression was found on days 2-3 of the cycle (p
- Subjects :
- endocrine system
medicine.medical_specialty
ADIPOR2 Gene
Sus scrofa
Hypothalamus
Gene Expression
Estrous Cycle
Luteal phase
Biology
Gonadotropin-Releasing Hormone
Endocrinology
Internal medicine
medicine
Animals
RNA, Messenger
Receptor
Adiponectin receptor 1
Estrous cycle
Adiponectin receptor 2
Adiponectin
Median eminence
Female
Animal Science and Zoology
Receptors, Adiponectin
Biotechnology
Subjects
Details
- ISSN :
- 09366768
- Volume :
- 49
- Database :
- OpenAIRE
- Journal :
- Reproduction in Domestic Animals
- Accession number :
- edsair.doi.dedup.....7620f5d9f6d0addc1e4f650a7f23bbea
- Full Text :
- https://doi.org/10.1111/rda.12282