Back to Search
Start Over
Impact of previous myocardial infarction on the incremental value of myocardial contrast to two-dimensional supine bicycle stress echocardiography in evaluation of coronary artery disease
- Source :
- International Journal of Cardiology. 136:47-55
- Publication Year :
- 2009
- Publisher :
- Elsevier BV, 2009.
-
Abstract
- If compared to two-dimensional echocardiography (2DE), myocardial contrast echocardiography (MCE) improves detection of coronary artery disease (CAD) during pharmacological stress, but data on MCE vs. 2DE during supine bicycle stress is limited. Although previous myocardial infarction (MI) influences sensitivity of 2DE, its effect on MCE has not been evaluated.The study sought to determine the incremental benefit of MCE over 2DE for evaluation of CAD during supine bicycle stress and to assess the impact of previous MI on diagnostic values of both methods.We studied 103 consecutive patients scheduled for coronary angiography. Prior to coronary angiography, all patients underwent supine bicycle stress. 2DE and MCE were performed during this stress test. The diagnosis of obstructive CAD (or =50% stenosis) was based on the presence of inducible wall motion and perfusion abnormalities.Quantitative coronary angiography revealedor =50% stenosis in 53 of 77 patients without previous MI and in 21 of 26 patients with previous MI. If compared to 2DE, MCE was more sensitive (68% vs. 86%; p0.001) and more accurate (73% vs. 86%; p0.001) to detector =50% stenosis. In patients without previous MI, 2DE and MCE yielded sensitivity of 65% and 85% (p0.01) and accuracy of 71% and 85% (p0.01), whereas in patients with previous MI sensitivity was 79% and 90% (p=NS) and accuracy 79% and 88% (p = NS), respectively.MCE enhances sensitivity and accuracy of 2DE in detection of obstructive CAD during supine bicycle stress. The incremental benefit of MCE is especially present in patients without previous MI.
- Subjects :
- Male
medicine.medical_specialty
Supine position
Myocardial Infarction
Coronary Artery Disease
Sensitivity and Specificity
Coronary artery disease
Internal medicine
Supine Position
medicine
Stress Echocardiography
Humans
Myocardial infarction
Aged
business.industry
Middle Aged
medicine.disease
Myocardial contrast echocardiography
Stenosis
Exercise Test
Cardiology
Female
Radiology
Myocardial infarction diagnosis
Cardiology and Cardiovascular Medicine
business
Perfusion
Echocardiography, Stress
Subjects
Details
- ISSN :
- 01675273
- Volume :
- 136
- Database :
- OpenAIRE
- Journal :
- International Journal of Cardiology
- Accession number :
- edsair.doi.dedup.....75dc5b03c89ff8738ede21a75a9c7f86