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ADC, D, f dataset calculated through the simplified IVIM model, with MGMT promoter methylation, age, and ECOG, in 38 patients with wildtype IDH glioblastoma
- Source :
- Data in Brief, Data in Brief, Vol 35, Iss, Pp 106950-(2021)
- Publication Year :
- 2021
-
Abstract
- Patients undergoing standard chemoradiation post-resection had MRIs at radiation planning and fractions 10 and 20 of chemoradiation. MRIs were 1.5T and 3D T2-FLAIR, pre- and post-contrast 3D T1-weighted (T1) and echo planar DWI with three b-values (0, 500, and 1000s/mm2) were acquired. T2-FLAIR was coregistered to T1C images. Non-overlapping T1 contrast-enhancing (T1C) and nonenhancing T2-FLAIR hyperintense regions were segmented, with necrotic/cystic regions, the surgical cavity, and large vessels excluded. The simplified IVIM model was used to calculate voxelwise diffusion coefficient (D) and perfusion fraction (f) maps; ADC was calculated using the natural logarithm of b = 1000 over b = 0 images. T1C and T2-FLAIR segmentations were brought into this space, and medians calculated. MGMT promoter methylation status (MGMTPMS), age at diagnosis, and Eastern Cooperative Oncology Group (ECOG) performance status were extracted from electronic medical records. The data were presented, analyzed, and described in the article, “Intravoxel incoherent motion (IVIM) modeling of diffusion MRI during chemoradiation predicts therapeutic response in IDH wildtype Glioblastoma”, published in Radiotherapy and Oncology [1] .
- Subjects :
- Science (General)
medicine.medical_treatment
Computer applications to medicine. Medical informatics
R858-859.7
Perfusion fraction
Radiation planning
03 medical and health sciences
Q1-390
0302 clinical medicine
Recurrence
Promoter methylation
medicine
Overall survival
Progression-free survival
Diffusion coefficient
Intravoxel incoherent motion
030304 developmental biology
Data Article
0303 health sciences
Multidisciplinary
Performance status
business.industry
medicine.disease
Radiation therapy
ADC
Simplified IVIM
Progression free survival
Nuclear medicine
business
Glioblastoma
030217 neurology & neurosurgery
Diffusion MRI
Subjects
Details
- ISSN :
- 23523409
- Volume :
- 35
- Database :
- OpenAIRE
- Journal :
- Data in brief
- Accession number :
- edsair.doi.dedup.....75db21c2f0de093c2efc967d9be329be