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Elevated triglycerides levels in two infants with hypoxic-ischemic encephalopathy undergoing therapeutic hypothermia and receiving parenteral nutrition
- Source :
- JPEN. Journal of parenteral and enteral nutrition. 38(6)
- Publication Year :
- 2012
-
Abstract
- Therapeutic hypothermia has been widely applied to improve the survival/neurodevelopmental outcomes among infants with moderate-to-severe hypoxic ischemic encephalopathy (HIE). Due to their critical condition and concerns over feeding tolerance, it is not uncommon to withhold enteral feeds and provide parenteral nutrition (PN) during hypothermia and early rewarming. Here we report 2 infants with HIE undergoing therapeutic hypothermia, and receiving PN, who exhibited early elevated triglyceride levels. Hypertriglyceridemia can be associated with neurologic complications, ranging from altered mental status, or irritability to seizures. Given the possible altered lipid metabolism under hypothermic conditions, we advocate close monitoring of lipid tolerance and conducting further prospective trials to elucidate lipid metabolism in these infants.
- Subjects :
- Male
Parenteral Nutrition
Medicine (miscellaneous)
Irritability
Hypoxic Ischemic Encephalopathy
chemistry.chemical_compound
Altered Mental Status
Hypothermia, Induced
Medicine
Humans
Triglycerides
Hypertriglyceridemia
Nutrition and Dietetics
Triglyceride
business.industry
Infant
Lipid metabolism
Hypothermia
medicine.disease
Parenteral nutrition
chemistry
Anesthesia
Hypoxia-Ischemia, Brain
Female
medicine.symptom
business
Subjects
Details
- ISSN :
- 19412444
- Volume :
- 38
- Issue :
- 6
- Database :
- OpenAIRE
- Journal :
- JPEN. Journal of parenteral and enteral nutrition
- Accession number :
- edsair.doi.dedup.....75961e3d2ba933d7cbf19a49a9e5c3e8