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6,6′-Bis(2-hydroxyphenyl)-2,2′-bipyridine manganese(III) complexes: A novel series of superoxide dismutase and catalase mimetics

Authors :
Ian B. Campbell
George E. Tranter
Ashley Paul Hancock
Christopher R Molloy
Karl Huffman
Gary I. Mills
Philip Charles Box
Ann Louise Walker
Gerard Martin Paul Giblin
Susan R. Doctrow
Susan Roomans
Bernard Malfroy
Source :
Bioorganic & Medicinal Chemistry Letters. 11:1367-1370
Publication Year :
2001
Publisher :
Elsevier BV, 2001.

Abstract

A series of novel manganese(III) complexes is described based on a 6,6'-bis(2-hydroxyphenyl)-2,2'-bipyridine template. These complexes show superoxide dismutase and catalase activity. The effect of the aromatic substitution pattern on the SAR is described.

Details

ISSN :
0960894X
Volume :
11
Database :
OpenAIRE
Journal :
Bioorganic & Medicinal Chemistry Letters
Accession number :
edsair.doi.dedup.....7571c04c73231f3fe42a9ae7f2d56f34
Full Text :
https://doi.org/10.1016/s0960-894x(01)00217-7