Thrombotic Thrombocytopenic Purpura and Hemolytic Uremic Syndrome

Thrombocytopenia and microangiopathic hemolytic anemia (MAHA) with schistocytes on the blood smear are key findings in thrombotic microangiopathies (TMAs). Initial clinical evaluation of patients focuses on the distinction between primary and secondary TMA forms associated with underlying diseases or systemic disorders.