Efficacy and safety of fixed combinations of latanoprost/timolol and dorzolamide/timolol in open-angle glaucoma or ocular hypertension

Authors :: Miglior, S.
Grunden, J. W.
Kwok, K.
Denis, P
Mouriaux, F
Peigne, G
Ridings, B
Rigal, D
Christ, T
Deuker, H
Hamacher, T
Hoffmann, M
Jelinek, C
Scherzer, Ml
Karabatsas, K
Konstas, A
Kozombolis, V
Tsilimbaris, M
Carassa, R
Delle Noci, N
Iester, M
Mastropasqua, L
Miglior, S
Nardi, Marco
Chatila, A
Heijl, A
Lindblom, B
Vancea, L.
Miglior, S
Grunden, J
Kwok, K
Source :: Eye. 24:1234-1242
Publication Year :: 2009
Publisher :: Springer Science and Business Media LLC, 2009.
Abstract: Aims To compare intraocular pressure (IOP) reductions with fixed-combination (FC) latanoprost/timolol once daily in the evening vsFC dorzolamide/timolol twice daily. Methods This evaluator-masked, multicentre, controlled clinical trial randomized subjects with primary open-angle glaucoma or ocular hypertension with IOP insufficiently responsive to Β-blocker therapy (screening IOP>21 and

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