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Malignant Post-Transplant Lymphoproliferative Disorder of Nasopharynx in Myelodysplastic Disorder
- Source :
- Healthcare, Vol 9, Iss 217, p 217 (2021), Healthcare
- Publication Year :
- 2021
- Publisher :
- MDPI AG, 2021.
-
Abstract
- (1) Background: Post-transplant lymphoproliferative disorder (PTLD) is a hematological disease and occurs because of immunosuppression after organ transplantation. Only a few studies have reported PTLD in the nasopharynx. In most cases, PTLD developed after solid organ transplantation, and cases of PTLD after bone marrow transplantation, are uncommon. (2) Case presentation: We report the case of a 40-year-old woman with myelodysplastic disorder who underwent hematopoietic stem cell transplantation (HSCT). After 3 months, she developed low-grade fever, progressive nasal obstruction, and bloody rhinorrhea. Endoscopy revealed a mass completely occupying the nasopharynx. A polymorphic PTLD was diagnosed on the basis of histopathological examination results. Reduction in immunosuppression and low-dose radiotherapy were prescribed for treatment. After a 3-year follow-up, no recurrence of PTLD or myelodysplastic disorder was detected. (3) Conclusions: While nasopharyngeal PTLD is rare, a routine examination of the nasopharynx should be considered in the post-transplant follow-up of patients for early detection and treatment of PTLD.
- Subjects :
- medicine.medical_specialty
Leadership and Management
medicine.medical_treatment
lcsh:Medicine
Case Report
lymphoma
Health Informatics
hematogenic disorder
Hematopoietic stem cell transplantation
Gastroenterology
Post-transplant lymphoproliferative disorder
Organ transplantation
polymorphism
nasopharynx
03 medical and health sciences
0302 clinical medicine
Health Information Management
hemic and lymphatic diseases
Internal medicine
medicine
030223 otorhinolaryngology
030304 developmental biology
0303 health sciences
rhinorrhea
medicine.diagnostic_test
business.industry
Health Policy
lcsh:R
Immunosuppression
medicine.disease
Endoscopy
Lymphoma
Radiation therapy
PTLD
surgical procedures, operative
medicine.symptom
business
Subjects
Details
- ISSN :
- 22279032
- Volume :
- 9
- Database :
- OpenAIRE
- Journal :
- Healthcare
- Accession number :
- edsair.doi.dedup.....74ee5129948e0e72ca1a2c091c706ec5
- Full Text :
- https://doi.org/10.3390/healthcare9020217