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Constitutive relationships of fabric, density, and elastic properties in cancellous bone architecture
- Source :
- Bone, 25, 4, pp. 481-486, Bone, 25(4), 481-486. Elsevier, Bone, 25, 481-486
- Publication Year :
- 1999
-
Abstract
- The hypothesis that trabecular morphology can predict the elastic properties of cancellous bone has only partly been verified and no predictive analytical model is currently available. Such models are becoming increasingly relevant as the resolution levels of three-dimensional scanning techniques approach the size of trabeculae. This study took advantage of micro-finite-element methods and tested the aforementioned hypothesis in normal cancellous bone material collected at six anatomical locations from 56 individuals. Numerical analysis was based on high-resolution three-dimensional computer reconstructions of cancellous bone specimens from which the complete elastic characteristics and trabecular morphology, represented by three different fabric measures (the mean intercept length and two volume-based ones), were calculated. Each fabric measure was analyzed individually using the tensorial relationships derived by Cowin (Mech Mater 4:137-147; 1985). Models for both stiffness and compliance entries were developed. The models based on stiffness entries could explain 93.4%-95.6% of the variance, whereas those based on compliance entries could explain 89.2%-89.4%. When using the former model, the MIL (mean intercept length measure) performed slightly better than the two volume-based measures, VO (volume orientation) and SVD (star volume distribution), with 23% less remaining variance. The high correlations found strongly support the hypothesis and increase the hope that, on the basis of information on trabecular morphology, it will be possible to obtain considerably better estimates of bone quality in vivo compared with the rough two-dimensional density measurements used today. [Journal Article; In English; United States]
- Subjects :
- Adult
Male
Histology
Adolescent
Physiology
Endocrinology, Diabetes and Metabolism
Models, Biological
Bone and Bones
Mean intercept length
Bone Density
Bone quality
medicine
The relationship between structure and functional loading of trabecular bone
Humans
Computer Simulation
Elasticity (economics)
De relatie tussen structuur en functionele belasting van trabeculair bot
Mathematics
Aged
Aged, 80 and over
Numerical analysis
Mathematical analysis
Biomechanics
Stiffness
Middle Aged
Finite element method
Elasticity
Biomechanical Phenomena
medicine.anatomical_structure
Female
medicine.symptom
Cancellous bone
Subjects
Details
- ISSN :
- 87563282
- Volume :
- 25
- Database :
- OpenAIRE
- Journal :
- Bone
- Accession number :
- edsair.doi.dedup.....74d7bf7a0d42914c682eea98750616ec