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Serotypic similarity and diversity of rotaviruses of mammalian and avian origin as studied by plaque-reduction neutralization
- Source :
- The Journal of infectious diseases. 149(5)
- Publication Year :
- 1984
-
Abstract
- A total of 16 different strains of rotavirus derived from seven mammalian species (four each from human and porcine species, two each from equine and simian species, and one each from canine and bovine species) and two avian species (one each from turkeys and chickens) were examined in plaque-reduction neutralization tests. Seven antigenically distinct serotypes were established on the basis of a greater than or equal to 20-fold difference between titers of homologous and heterologous reciprocal neutralizing antibodies. Serotypes 1 (strain Wa) and 2 (strain DS-1) were recovered only from humans. Serotype 3 included human rotavirus strain WALK 57/14, rhesus monkey rotavirus strain MMU18006 , vervet monkey rotavirus strain SA-11, dog rotavirus strain CU-1, and horse rotavirus strain H-2. The newly established serotype 4 was identified in both humans (strain St. Thomas no. 4) and pigs (strains Gottfried , SB-1A, and SB-2). Porcine (strain OSU ) and equine (strain H-1) rotaviruses made up a possible fifth serotype. Bovine rotavirus (strain NCDV) constituted a sixth serotype, and chicken rotavirus (strain Ch 2), which had a prime-strain relation with turkey rotavirus (strain Ty 1), was designated serotype 7. A surprising observation that emerged from this study was the existence of a rotavirus (porcine strain SB-1A) bridging serotypes 4 and 5.
- Subjects :
- Serotype
Rotavirus
Turkeys
Swine
viruses
Heterologous
Simian
medicine.disease_cause
Neutralization
Epitopes
Dogs
Neutralization Tests
medicine
Immunology and Allergy
Animals
Humans
Vervet monkey
Horses
Serotyping
Antigens, Viral
RNA, Double-Stranded
Strain (chemistry)
biology
virus diseases
Haplorhini
biology.organism_classification
Virology
Titer
Infectious Diseases
RNA, Viral
Cattle
Electrophoresis, Polyacrylamide Gel
Chickens
Subjects
Details
- ISSN :
- 00221899
- Volume :
- 149
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- The Journal of infectious diseases
- Accession number :
- edsair.doi.dedup.....74aacabf41ea8f4c08a8d38e4cc14dbf