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Multiple common variants for celiac disease influencing immune gene expression
- Source :
- Nature genetics, Nature genetics, vol 42, iss 4, Nature Genetics, 42(4), 295, Dubois, P C, Trynka, G, Franke, L, Hunt, K A, Romanos, J, Curtotti, A, Zhernakova, A, Heap, G A, Adany, R, Aromaa, A, Bardella, M T, Van den Berg, L H, Bockett, N A, de la Concha, E G, Dema, B, Fehrmann, R S, Fernandez-Arquero, M, Fiatal, S, Grandone, E, Green, P M, Groen, H J, Gwilliam, R, Houwen, RH, Hunt, S E, Kaukinen, K, Kelleher, D, Korponay-Szabo, I, Kurppa, K, MacMathuna, P, Maki, M, Mazzilli, M C, McCann, O T, Mearin, M L, Mein, C A, Mirza, M M, Mistry, V, Mora, B, Morley, K I, Mulder, C J J, Murray, J A, Nunez, C, Oosterom, E, Ophoff, R A, Polanco, I, Peltonen, L, Platteel, M, Rybak, A, Salomaa, V, Schweizer, J J, Sperandeo, M P, Tack, G J, Turner, G, Veldink, J H, Verbeek, W H M, Weersma, R K, Wolters, V M, Urcelay, E, Cukrowska, B, Greco, L, Neuhausen, S L, McManus, R, Barisani, D, Deloukas, P, Barrett, J C, Saavalainen, P, Wijmenga, C & van Heel, D A 2010, ' Multiple common variants for celiac disease influencing immune gene expression ', Nature Genetics, vol. 42, no. 4, pp. 295-302 . https://doi.org/10.1038/ng.543, Nature Genetics, 42(4), 295-U42. Nature Publishing Group, Nature Genetics, 42(4), 295-302. Nature Publishing Group
- Publication Year :
- 2010
-
Abstract
- We performed a second-generation genome-wide association study of 4,533 individuals with celiac disease (cases) and 10,750 control subjects. We genotyped 113 selected SNPs with P(GWAS)
- Subjects :
- POSITIVE SELECTION
HETERODIMER
Genes, MHC Class I
Gene Expression
Genome-wide association study
Medical and Health Sciences
MHC Class I
0302 clinical medicine
Immunopathology
RISK VARIANTS
2.1 Biological and endogenous factors
Aetiology
POPULATION
Genetics
0303 health sciences
education.field_of_study
THYMUS
Orvostudományok
Single Nucleotide
THYMOCYTES
Biological Sciences
3. Good health
030220 oncology & carcinogenesis
Egészségtudományok
Human
Biotechnology
Risk
SUSCEPTIBILITY LOCI
Population
Single-nucleotide polymorphism
CLEC16A
Quantitative trait locus
Biology
Polymorphism, Single Nucleotide
Article
03 medical and health sciences
Meta-Analysis as Topic
Humans
Allele
GENOME-WIDE ASSOCIATION
Polymorphism
education
030304 developmental biology
Gene Expression Profiling
Human Genome
BIO/13 - BIOLOGIA APPLICATA
ALLELES
RHEUMATOID-ARTHRITIS
Gene expression profiling
Celiac Disease
Genes
Case-Control Studies
genome-wide association rheumatoid-arthritis susceptibility loci positive selection risk variants population alleles thymus heterodimer thymocytes
Digestive Diseases
Genome-Wide Association Study
Developmental Biology
Subjects
Details
- Language :
- English
- ISSN :
- 15461718 and 10614036
- Volume :
- 42
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- Nature genetics
- Accession number :
- edsair.doi.dedup.....74aab4d937fd5cb03fec3a1adcce0bdf
- Full Text :
- https://doi.org/10.1038/ng.543