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Impact of sleep on complicated grief severity and outcomes
- Source :
- Depress Anxiety
- Publication Year :
- 2019
-
Abstract
- BACKGROUND Complicated grief (CG) is characterized by persistent, impairing grief after losing a loved one. Little is known about sleep disturbance in CG. Baseline prevalence of subjective sleep disturbance, impact of treatment on sleep, and impact of mid-treatment sleep on CG and quality of life outcomes were examined in adults with CG in secondary analyses of a clinical trial. METHODS Patients with CG (n = 395, mean age =53.0; 78% female) were randomized to CGT+placebo, CGT+citalopram (CIT), CIT, or placebo. Subjective sleep disturbance was assessed by a grief-anchored sleep item (Pittsburgh Sleep Quality Index: PSQI-1) and a four-item sleep subscale of the Quick Inventory of Depressive Symptomatology (QIDS-4). Sleep disturbance was quantified as at least one QIDS-4 item with severity ≥2 or grief-related sleep disturbance ≥3 days a week for PSQI-1. Outcomes included the Inventory of Complicated Grief (ICG), Work and Social Adjustment Scale (WSAS), and Clinical Global Impressions Scale. RESULTS Baseline sleep disturbance prevalence was 91% on the QIDS-4 and 46% for the grief-anchored PSQI-1. Baseline CG severity was significantly associated with sleep disturbance (QIDS-4: p = .015; PSQI-1: p = .001) after controlling for comorbid depression and PTSD. Sleep improved with treatment; those receiving CGT+CIT versus CIT evidenced better endpoint sleep (p = .027). Mid-treatment QIDS-4 significantly predicted improvement on outcome measures (all p
- Subjects :
- Male
Sleep Wake Disorders
medicine.medical_specialty
media_common.quotation_subject
Poison control
Comorbidity
Citalopram
Article
Pittsburgh Sleep Quality Index
03 medical and health sciences
0302 clinical medicine
Quality of life
Sleep Initiation and Maintenance Disorders
medicine
Humans
media_common
Sleep disorder
business.industry
Depression
Middle Aged
medicine.disease
Sleep in non-human animals
Complicated grief
humanities
030227 psychiatry
Psychiatry and Mental health
Clinical Psychology
Treatment Outcome
Physical therapy
Quality of Life
Grief
Female
business
Sleep
030217 neurology & neurosurgery
Bereavement
Subjects
Details
- ISSN :
- 15206394
- Volume :
- 37
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Depression and anxiety
- Accession number :
- edsair.doi.dedup.....7468fa4f0d162950d674b2521bb9daf2